Abstract:Objective To investigate imaging anatomical features and factors affecting tortuous basilar artery in healthy adult using magnetic resonance angiography (MRA).Methods MRA data of 160 healthy adults with tortuous basilar artery, who examined in Beijing Fengtai Hospital from March 2015 to May 2016, were retrospectively analyzed. There were 99 males and 61 females, aged from 30 to 65 years. The morphology and direction of the basilar artery and the intracranial vertebral artery were observed on the MIP image reconstructed by MRA.Results In 160 adults with tortuous basilar artery, 104 (65.0%), 56(35.0%) adults were found to be the basilar artery bending to the right and left respectively, and there was significantly statistical difference. Among 104 adults with a basilar artery bending to right, 84(80.8%) had a dominant left vertebral artery, and among 56 adults with a basilar artery bending to left, 23(41.1%) had a dominant right vertebral artery, there was significantly statistical difference (P<0.01). In 20 adults with basilar artery bending to the right not accompanied dominant left vertebral artery, 13(65.0%) cases had an asymmetrical direction before bilateral vertebral artery confluence, and 7(35.0%) cases had a symmetrical direction. Eight (40.0%) cases of bilateral vertebral artery confluence deviated to the left, and 2(20.0%) cases to the right, 10(50.0%) cases in the middle. Thirty-three adults with basilar artery bending to the left not accompanied dominant right vertebral artery, 23 (69.7%) cases had an asymmetrical direction before bilateral vertebral artery confluence, and 10(30.3%) cases had a symmetrical direction. Thirteen (39.4%) cases of bilateral vertebral artery confluence deviated to left, and 6(18.2%) cases to the right ,14(42.4%) cases in the middle. There was no significantly statistical difference (all P values>0.05) in the direction and confluence position of bilateral vertebral artery between the two groups.Conclusions The healthy adults with tortuous basilar artery mostly accompanied with variability of vertebral artery dominance. Because of its hemodynamic characteristics, vertebral artery dominance is one of anatomical factors affecting basilar artery.
李学军, 崔平, 蔡玉, 秦宝琦, 尚璟超. 健康体检成人基底动脉弯曲的磁共振血管成像影像解剖学特征[J]. 中华解剖与临床杂志, 2018, 23(6): 469-472.
Li Xuejun, Cui Ping, Cai Yu, Qin Baoqi, Shang Jingtao.. The magnetic resonance angiography imaging anatomy characters of tortuous basilar artery in healthy adults. Chinese Journal of Anatomy and Clinics, 2018, 23(6): 469-472.
Lou M, Caplan LR. Vertebrobasilar dilatative arteriopathy (dolichoectasia)[J]. Ann N Y Acad Sci, 2010, 1184: 121-133. DOI:10.1111/j.1749-6632.2009.05114.x
[3]
Ubogu EE, Zaidat OO. Vertebrobasilar dolichoectasia diagnosed by magnetic resonance angiography and risk of stroke and death: a cohort study[J]. J Neurol Neurosurg Psychiatry, 2004, 75(1): 22-26
[4]
Giang DW, Perlin SJ, Monajati A, et al. Vertebrobasilar dolichoectasia: assessment using MR[J]. Neuroradiology, 1988, 30(6): 518-523
[5]
Hong JM, Chung CS, Bang OY, et al. Vertebral artery dominance contributes to basilar artery curvature and peri-vertebrobasilar junctional infarcts[J]. J Neurol Neurosurg Psychiatry, 2009, 80(10): 1087-1092. DOI:10.1136/jnnp.2008.169805
Cunningham KS, Gotlieb AI. The role of shear stress in the pathogenesis of atherosclerosis[J]. Lab Invest, 2005, 85(1): 9-23. DOI:10.1038/labinvest.3700215
[8]
Bevan RD, Vijayakumaran E, Gentry A, et al. Intrinsic tone of cerebral artery segments of human infants between 23 weeks of gestation and term[J]. Pediatr Res, 1998, 43(1): 20-27. DOI:10.1203/00006450-199804001-00125
[9]
Lamblin N, Bauters C, Hermant X, et al. Polymorphisms in the promoter regions of MMP-2, MMP-3, MMP-9 and MMP-12 genes as determinants of aneurysmal coronary artery disease[J]. J Am Coll Cardiol, 2002, 40(1): 43-48. DOI:10.1016/S0735-1097(02)01909-5
[10]
Stroud JS, Berger SA, Saloner D. Influence of stenosis morphology on flow through severely stenotic vessels: implications for plaque rupture[J]. J Biomech, 2000, 33(4): 443-455. DOI: 10.1016/S0021-9290(99)00207-9