Abstract:Objective To investigate the safety and efficacy of stenting for symptomatic intracranial artery stenosis.Methods A retrospective analysis was conducted. Clinical data of 31 patients who underwent intracranial atherosclerotic stent implantation in the Department of Neurology of the First Affiliated Hospital of Army Medical University from September 2014 to August 2015 were included. The patients comprised 21 males and 10 females, aged 36-73 years old (mean, 57.00±9.87 years old). According to the stent type, the patients were divided into the self-expanding stent group (16 cases) and the balloon-mounted stent group (15 cases). Patients were followed up for more than 5 years, and endpoint events were observed and recorded. The endpoint events that occurred within 30 days after stenting events included stroke, transient ischemic attack, and death. The endpoint events that occurred 30 days to 5 years after stenting included ipsilateral ischemic stroke, cerebral hemorrhage, and vascular death.Results Thirty-one patients were followed up for 1-77 months (mean, 62.7±15.5 months). Four patients had endpoint events, including three deaths, within 5 years. Two cases of cerebral hemorrhage had endpoint events within 30 days after surgery, including 1 death. Two patients developed endpoint events in 30 days to 5 years; 2, 2, 4, 4, and 4 cumulative endpoint events occurred in 1 to 5 years, among them, 2 cases were increased in 3 years, 1 was ipsilateral ischemic stroke, and 1 was hemorrhagic stroke; all these patients died. No statistically significant difference was found between the self-expanding stent group and the balloon-mounted stent group for each endpoint event (all P values>0.05).Conclusions Stenting for symptomatic intracranial arterial stenosis is safe and effective in both perioperative and long-term follow-up periods.
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