Effect of operative duration on postoperative efficacy of laparoscopic D3 radical resection for advanced right colon cancer
Huang Haipeng, Xiong Wenjun, Zheng Yansheng, Luo Lijie, Li Jin, Cui Ziming, Wang Wei
Department of Gastrointestinal Surgery, the Second Affiliated Hospital, Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangdong 510030, China
Abstract：Objective To study the effect of the operative duration on postoperative clinical efficacy of laparoscopic D3 radical resection for advanced right colon cancer.Methods This study is a cross-sectional study. Ninety-four patients with advanced right colon cancer in Guangdong Hospital of Traditional Chinese Medicine from January 2018 to August 2020 were included. The patients comprised 46 males and 48 females, including 45 and 49 patients in stages Ⅱ and Ⅲ, respectively, aged 16-93 (64.2±16.1) years. All patients successfully underwent laparoscopy-assisted D3 radical resection of right colon cancer. The operation duration was in the range of 100-327 (198.9±53.4) min. Four time nodes based on the length of operation time of the patients, namely, the 20th (152 min), 40th (180 min), 60th (205 min), and 80th percentiles (237 min), were divided into two groups ≤ the duration of the node and > the duration of the node. The clinical baseline data of patients in each group were compared, and perioperative indicators, including intraoperative blood loss, first postoperative exhaust time, postoperative hospital stay, and postoperative complications, were observed.Results The operation was successfully performed in all patients, no operation was converted to open surgery, and no intraoperative death occurred during hospitalization. The intraoperative blood loss was 10-200 mL, the first exhaust time was 1-5 days, and the postoperative hospital stay was 3-21 days. Postoperative complications included respiratory tract infection in three cases, incision infection in four cases, anastomotic leakage in two cases, abdominal effusion in four cases, and intestinal obstruction in two cases. Comparison of clinical baseline data showed no significant differences in gender, age, tumor size, and BMI among all groups (all P values >0.05). Significant differences in tumor stage were found in the 60th and 80th percentile arrays (χ2=6.79, 6.86; all P values <0.05). Comparison of perioperative indicators showed significant differences in postoperative hospital stay in the 60th percentile array, as well as the first exhaust time, postoperative hospital stay, and total postoperative complication rate in the 80th percentile array (all P values <0.05), but no significant differences were found in the other observation indexes in each group (all P values >0.05).Conclusion The postoperative recovery time and the incidence of complications increase in patients with advanced right colon cancer who undergo laparoscopic D3 radical resection with the prolongation of operation time.
黄海鹏, 熊文俊, 郑燕生, 罗立杰, 李金, 崔梓铭, 王伟. 进展期右半结肠癌腹腔镜D3根治术手术时长对术后疗效的影响[J]. 中华解剖与临床杂志, 2023, 28(1): 56-60.
Huang Haipeng, Xiong Wenjun, Zheng Yansheng, Luo Lijie, Li Jin, Cui Ziming, Wang Wei. Effect of operative duration on postoperative efficacy of laparoscopic D3 radical resection for advanced right colon cancer. Chinese Journal of Anatomy and Clinics, 2023, 28(1): 56-60.
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2023, Vol. 28 
