Abstract：Objective This study aimed to explore the application value of personalized hybridization in the treatment of complex lower extremity arteriosclerosis obliterans (LEASO).Methods Retrospective analysis was performed on the clinical data of 26 patients with complex multi-segmental LEASO at the Vascular Surgery Department of the First Affiliated Hospital of Bengbu Medical College from July 2016 to September 2018. A total of 17 males and 9 females, aged between 45 and 88 (66.4±10.8) years, were included in this study. Ankle brachial index (ABI), intermittent claudication distance, and primary patency rate were observed.Results The success rate of hybrid surgery was 100% in 26 patients, no serious complications occurred during and after the operation, symptoms of lower limb ischemia were improved, and the examination of postoperative ABI was significantly improved compared with that before the operation. The average ABI of the affected limbs increased to 0.89±0.14, which was significantly higher than 0.41±0.46 before the operation, with statistically significant difference(t=5.151, P<0.05). The distance of intermittent claudication was (523±56) m, which was significantly longer than (132±46) m before the operation, and the difference was statistically significant(t=4.982, P<0.05). All 26 patients were followed up for 12 months. The primary patency rate was 92.30% (24/26), the limb salvage rate was 100% (26/26), and the survival rate was 100% (26/26). The primary patency rate was 76.92% (20/26), the limb salvage rate was 92.30% (24/26), and the survival rate was 100%(26/26).Conclusions For complex LEASO involving multiple segments, individualized hybrid surgical approach is safe and effective with increased patient benefit.
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Tang Wenbo, Gao Yong, Yu Chaowen, Nie Zhonglin, Chen Shiyuan, Song Tao, Lu Ran, Sun Yong, Guan Zeyu, Wang Xiaogao, Xu Chao. The application value of hybridization in the treatment of complicated lower extremity arteriosclerosis obliterans. Chinese Journal of Anatomy and Clinics, 2020, 25(4): 401-405.
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2020, Vol. 25 
