咽喉反流对会厌囊肿的影响分析

doi:10.3760/cma.j.cn101202-20210922-00265

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摘要目的探讨咽喉反流对会厌囊肿的影响。方法回顾性研究。纳入2020年11月—2021年5月蚌埠医学院第一附属医院耳鼻咽喉科头颈外科电子喉镜检查的170例患者的临床资料。其中,会厌囊肿患者79例（会厌囊肿组）,男29例、女50例,年龄（50±12）岁;会厌正常者91例（对照组）,男40名、女51名,年龄（47±10）岁。咽喉反流的判定采用反流症状指数（RSI）量表、反流体征评分（RFS）量表（RSI>13分和/或RFS>7分）。将性别、年龄、吸烟、饮酒、咽喉反流、辛辣饮食、职业暴露纳入单因素分析,分析会厌囊肿的影响因素;多因素采用logistic回归分析。结果会厌囊肿组患者中存在咽喉反流38例（48.10%,38/79）,对照组中存在咽喉反流19例（20.88%,19/91）。单因素分析显示,咽喉反流、吸烟、辛辣饮食、职业暴露是会厌囊肿的影响因素,差异均有统计学意义（χ²=14.06、8.89、9.83、9.60,P值均<0.05）。进一步多因素logistic回归分析显示,咽喉反流（优势比=2.307,95%可信区间：1.104~4.820）及辛辣饮食（优势比=2.414,95%可信区间：1.241~4.698）为会厌囊肿的独立危险因素。结论咽喉反流和辛辣饮食是会厌囊肿的独立危险因素。为预防会厌囊肿的发生,应积极治疗咽喉反流。

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	李慧珺
	姚卫格
	江涛
	许亚佳
	蒋成义

关键词 ：会厌囊肿, 咽喉反流, 影响因素分析

Abstract：Objective To investigate the effect of laryngopharyngeal reflux on epiglottic cyst. Methods The retrospective study was performed using the clinical data of 170 patients examined by electronic laryngoscopy in the Department of Otorhinolaryngology of the First Affiliated Hospital of Bengbu Medical College from November 2020 to May 2021. Among them, 79 patients, including 29 males and 50 females aged (50±12) years, had epiglottic cyst (epiglottic cyst group). Ninety-one cases, including 40 males and 51 females aged (47±10) years, had normal epiglottis(control group). Reflux symptom index > 13 and reflux syndrome score > 7 were used to determine laryngopharyngeal refluxes. The influencing factors of epiglottic cyst (including gender, age, smoking, drinking, laryngopharyngeal reflux, spicy diet, and occupational exposure) were analyzed by univariate and multivariate logistic regression analyses. Results A total of 38 and 19 cases of laryngopharyngeal reflux were found in the epiglottic cyst group (48.10%, 38/79) and control group (20.88%, 19/91), respectively. Univariate analysis showed that laryngopharyngeal reflux, smoking, spicy diet, and occupational exposure were related to epiglottic cyst, and the differences were statistically significant (χ²=14.06, 8.89, 9.83, 9.60; all P values <0.05). Multivariate logistic regression analysis showed that laryngopharyngeal reflux (odds ratio [OR]=2.307, 95% confidence interval [CI]=1.104-4.820) and spicy diet (OR=2.414, 95% CI=1.241-4.698) were independent risk factors of epiglottic cyst. Conclusion Laryngopharyngeal reflux and spicy diet are independent risk factors of epiglottic cyst. Laryngopharyngeal reflux should be actively treated to prevent the occurrence of epiglottic cyst.

Key words： Epiglottic cyst Laryngopharyngeal reflux Root cause

收稿日期: 2021-09-22

通讯作者: 蒋成义,Email：jiangchengyi1975@163.com

引用本文:

李慧珺, 姚卫格, 江涛, 许亚佳, 蒋成义. 咽喉反流对会厌囊肿的影响分析[J]. 中华解剖与临床杂志, 2022, 27(6): 401-404.
Li Huijun, Yao Weige, Jiang Tao, Xu Yajia, Jiang Chengyi. Effect of laryngopharyngeal reflux on epiglottic cyst. Chinese Journal of Anatomy and Clinics, 2022, 27(6): 401-404.

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http://www.cjac.com.cn/CN/10.3760/cma.j.cn101202-20210922-00265 或 http://www.cjac.com.cn/CN/Y2022/V27/I6/401

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