Abstract:Objective:To study the pernicious placenta praevia for pregnant and lying-in woman so as to better understand the pernicious placenta praevia. Methods:23 women with pernicious placenta praevia were received from January 2003 to February 2012 as the observation group. The cesarean section amount of these patients were 1.7±0.4.Meanwhile 57 women without pernicious placenta praevia were taken as the control group.The cesarean section amount of these patients were 1.4±0.2. Comparative analysis of clinical data was conducted for the two groups.Results:Observation group: 14(60.87%) cases of adherent placenta and implantation; during cesarean section and postpartum hemorrhage of 20(86.96%) which amount of bleeding was (2785±263)ml; 14(60.87%) of panhysterectomy (one death accounted for 4.35%). Control group: 3(5.26%) cases of adherent placenta and implantation; during cesarean section and postpartum hemorrhage of 19(33.33%) which amount of bleeding was (850±340)ml; 3(5.26%) cases of panhysterectomy (zero death). The observation group had higher cesarean section amount, operation duration, incidence rate of adherent placenta and implantation, postpartum hemorrhage and panhysterectomy ratio than the control group. This difference had statistical significance (P<0.05). 45 cases in two groups had follow-up with duration of one or six months, 5 in average. In the follow-up, only one woman who had panhysterectomy bled a little in the vagina half month after the operation. However, she recovered after stopping the bleeding. The rest recovered well.Conclusions:Pernicious placenta praevia impacts the pregnant and lying-in woman severely. Reducing the amount of cesarean section will lower the incidence rate. The key to ensure the life safety of the pregnant and lying-in woman is to better understand the pernicious placenta praevia and select the correct methods in perioperative period.