Abstract：Objective To investigate the complications and its risk factors following pancreatoduodenectomy (PD) in the elderly patients. Methods Clinicopathological data of 65 elderly patients (age≥65 years), who were subject to PD in The First Affiliated Hospital, Sun Yat-Sen University between January 2010 and January 2013, were retrospectively analyzed. The post-operative complications and its risk factors were analyzed by uni-variate and multi-variate logistic analysis. Results There were 65 patients in the present series, and PD was successfully performed in all patients. The postoperative complications included intra-abdominal infection in 13, pancreatic leakage in 9, intra-abdominal bleeding in 4, bile leakage in 4, delayed gastric emptying in 2, wound infection in 2, pulmonary infection in 2, upper gastrointestinal bleeding in 1 and hydrothorax in 1, with the postoperative complications incidence of 41.5% (27/65). Five patients died within 1 month after operation, with a mortality of 7.7% (5/65). Multivariate logistic regression analysis revealed that independent risk factors for postoperative complications were soft texture of remnant pancreas and pancreatic duct diameter smaller than 3 mm (P＜0.05). Independent risk factors for postoperative intra-abdominal infection included intra-operative bleeding ≥400 ml and soft texture of remnant pancreas (P＜0.05). Independent risk factors for postoperative pancreatic leakage were operative time >360 min, soft texture of remnant pancreas and pancreatic duct diameter smaller than 3 mm (P＜0.05). Conclusions Senile age was not the contraindication for PD. The independent risk factors for post-operative morbidities were soft texture of remnant pancreas and pancreatic duct diameter smaller than 3 mm.
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2014, Vol. 19 
