Abstract：Objective To investigate the influence of the instrumentation growing rods of sliding pedicle screw system unilateral insertion on the growth of the spine in an animal model.Methods A total of 15 pigs (about 3-month age)were randomly assigned into 3 groups: group A, blank control group only exposing unilateral posterior lamellar; group B, unilateral inserting the traditional pedicle screw system; group C, unilateral inserting the instrumentation growing rods of sliding pedicle screw system. The average heights of T6~10, T10~14 and T6~10 dises, and the distance of both up-and down-ends of titanium rod sliding in group C were measured. X ray was used to examined the morphology of the spine. After 3-month observation, the animal samples are collected. selected segments of the fixed disc morphology was observed growth plate chondrocytes.Results Three months after operation,the average heights of T6~10[(26.81±1.70)mm], T10~14[(27.43±2.92)mm], T6~10 [(2.13±0.17)mm] discs and growth plate chondrocytes in group C had no remarkble difference from those in group A[(27.13±3.31)mm, (27.91±3.03)mm, (2.20±0.14)mm, all P values>0.05], but significantly larger than in group B[(22.30±2.52)mm, (22.62±2.11)mm, (0.82±0.41)mm, all P values<0.05]. Growth occurred in both up-and down-ends of the titanium rods for a total average of 42.7 mm. The average height of growth plate chondrocytes in group C [ (165.6±1.7) μm] had no remarkble difference in group A [ (167.2±6.8) μm, P＞0.05], but distinctly increased than that in group B [ (140.4±7.2) μm, P＜0.05].Conclusions The unilateral instrumentation growing rods of sliding pedicle screw system placement has no evident influence on the progression of the immature porcine spine.
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Xue Jingbo, Wang Wenjun, Zhong Jian, Yan Yiguo, Wang Lushan, Wang Cheng, Li Xuelin, Chen Lijuan. Effect of instrumentation growing rods of sliding pedicle screw system unilateral insertion on growth of immature porcine spine.. Chinese Journal of Anatomy and Clinics, 2014, 19(5): 376-380.
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