Finite element analysis of new design assembly locking compression plate with low modulus titanium alloy in the treatment of middle femoral comminuted fracture
Zhou Jiangjun*, Zhao Min, Yi Rui, Liu Da, Yang Jun, Cheng Qiuxin, Yu Zhuanyi, Fu Meiqing, Shi Bona, Lei Xue
*Department of Orthopedics, the 184th Hospital of PLA, Spinal surgery treatment center of Nanjing Military Region, Yingtan 335000, China
Abstract：Objective To explore the stress distribution of new design assembly locking compression plate (NALCP) with different modulus in the treatment of middle femoral comminuted fracture by finite element analysis (FEA). Methods A male volunteer received CT scanning with 0.625 mm slice thickness. The CT data was converted to middle femoral comminuted fracture FEA model by Mimics, Geomagic studio 12.0, etc. The femoral fracture was fixated by Ti-6Al-4V (high modulus group, E=110 GPa) and Ti2448 (low modulus group, E=30 GPa) respectively, and loads were applied on the three models to simulate a person slowly walking by one leg or torsion. The stress distribution of the plate and bone was observed. Results In two conditions, the stress distribution tendency of the three kinds of plates was uniformity roughly. The maximum stress was situated in the locking-hole which links the main plate and the runner plate. The stress forces of the main plate in two groups were almost the same. In two conditions of slow walking by one leg or torsion, compared with group Ti-6Al-4V, the maximum stress of runner plate in group Ti2448 were reduced 20.6% and 15.2%, and the axial maximum stress of the bone block were increased 95.8% and 95.7%. Conclusions NALCP with low modulus titanium alloy would provide adequate mechanical stability and stress stimulation, which would apt to fixate the bone block.
周江军,赵敏,易蕊,刘达,杨俊,程球新,余专一,付美清,史柏娜,雷雪. 低弹性模量新型组合式锁定加压钢板固定股骨粉碎性骨折的三维有限元分析[J]. 中华解剖与临床杂志, 2016, 21(3): 245-250.
Zhou Jiangjun, Zhao Min, Yi Rui, Liu Da, Yang Jun, Cheng Qiuxin, Yu Zhuanyi, Fu Meiqing, Shi Bona, Lei Xue. Finite element analysis of new design assembly locking compression plate with low modulus titanium alloy in the treatment of middle femoral comminuted fracture. Chinese Journal of Anatomy and Clinics, 2016, 21(3): 245-250.
Nassiri M, Macdonald B, O′byrne JM. Computational modelling of long bone fractures fixed with locking plates-How can the risk of implant failure be reduced?[J]. J Orthop, 2013, 10(1): 29-37. DOI:10.1016/j.jor.2013.01.001
Wu J, Liu ZM, Zhao XH, et al. Improved biological performance of microarc-oxidized low-modulus Ti-24Nb-4Zr-7.9Sn alloy[J]. J Biomed Mater Res B Appl Biomater, 2010, 92(2): 298-306. DOI:10.1002/jbm.b.31515
[6]
Lin DJ, Chuang CC, Chern Lin JH, et al. Bone formation at the surface of low modulus Ti-7.5Mo implants in rabbit femur[J]. Biomaterials, 2007, 28(16): 2582-2589. DOI:10.1016/j.biomaterials.2007.02.005
Koivumki JE, Thevenot J, Pulkkinen P, et al. Ct-based finite element models can be used to estimate experimentally measured failure loads in the proximal femur[J]. Bone, 2012, 50(4): 824-829. DOI:10.1016/j.bone.2012.01.012
[10]
Radcliffe I, Taylor M. Investigation into the affect of cementing techniques on load transfer in the resurfaced femoral head: A multi-femur finite element analysis[J]. Clinical Biomechanics, 2007, 22(4): 422-430. DOI:10.1016/j.clinbiomech.2006.12.001
Niikura T, Lee SY, Sakai Y, et al. Causative factors of fracture nonunion: the proportions of mechanical, biological, patient-dependent, and patient-independent factors[J]. J Orthop Sci, 2014, 19(1): 120-124. DOI:10.1007/s00776-013-0472-4
[13]
Frost HM. A 2003 update of bone physiology and Wolff′s Law for clinicians[J]. Angle Orthod, 2004, 74(1): 3-15
[14]
Steiner M, Claes L, Ignatius A, et al. Disadvantages of interfragmentary shear on fracture healing-mechanical insights through numerical simulation[J]. J Orthop Res, 2014, 32(7): 865-872. DOI:10.1002/jor.22617
[15]
Ueng SW, Shih CH. Augmentative plate fixation for the management of femoral nonunion with broken interlocking nail[J]. J Trauma, 1998, 45(4): 747-752
[16]
Choi YS, Kim KS. Plate augmentation leaving the nail in situ and bone grafting for non-union of femoral shaft fractures[J]. Int Orthop, 2005, 29(5): 287-290. DOI:10.1007/s00264-005-0668-0
[17]
Sigurdsen U, Reikeras O, Utvag SE. The influence of compression on the healing of experimental tibial fractures[J]. Injury, 2011, 42(10): 1152-1156. DOI:10.1016/j.injury.2010.08.018
Dragomir-Daescu D, Salas C, Uthamaraj S, et al. Quantitative computed tomography-based finite element analysis predictions of femoral strength and stiffness depend on computed tomography settings[J]. J Biomech, 2015, 48(1): 153-161. DOI:10.1016/j.jbiomech.2014.09.016
[20]
Jiang-Jun Z, Min Z, Ya-Bo Y, et al. Finite element analysis of a bone healing model: 1-year follow-up after internal fixation surgery for femoral fracture[J]. Pak J Med Sci, 2014, 30(2): 343-347
2016, Vol. 21 
