Abstract:Objective To discuss the brain glymphatic system physiology and mechanism and the research progress of application study in the related diseases.Methods The literatures about the brain glymphatic system at home and abroad from January 2013 to October 2016 were searched in PubMed by using “glymphatic” as key words.Results There is a clear internal brain metabolites (such as β-amyloid) as the glymphatic system, the system is based on the structure of radial glial cells, play roles in a variety of neurodegenerative diseases (such as cleaning β-amyloid).Conclusions The active glymphatic system can reduce the onset of neurodegenerative diseases, and the neurodegenerative disease has a good prevention effect.To make the glymphatic system better provide guidance for clinical, further analysis of the glymphatic system is needed.
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