Abstract:Objective This study aimed to compare the short-term efficacy of open surgery (OSR) and endovascular surgery (EVAR) for abdominal aortic aneurysm.Methods A retrospective analysis was conducted on 118 patients who underwent surgery in the Department of Vascular Surgery of the First Affiliated Hospital of Bengbu Medical College due to abdominal aortic aneurysm from January 2008 to December 2020. The patients comprised 102 males and 16 females aged 70.5±9.6 years. According to different surgical-treatment methods, 23 cases were divided into the OSR group, and 95 cases were divided into the EVAR group. The outcome measures were as follows. (1) The baseline data of age, gender, bad living habits, complications, tumor diameter, and complex tumor neck morphology were compared between the two groups. (2) The operation time, intraoperative bleeding, fasting time, postoperative bed time, hospital stay, postoperative complications, and death were compared between the two groups. (3) Computed tomography angiography was rechecked, and the presence of reintervention, stent thrombosis, stent restenosis, graft infection, and various types of internal leakage was noted.Results No significant difference in baseline data was observed between the OSR and EVAR groups (all P values>0.05). The operation was performed in all patients successfully. The operative time, intraoperative blood loss, water fasting time, postoperative bed time, and hospital stay in the EVAR group were all shorter than those in the OSR group: (141.15±22.97) min vs. (242.79±29.41) min, (34.32±16.08) mL vs. (443.93±109.58) mL, (14.26±3.34) h vs. (52.25±12.05) h, (4.07±0.63) d vs. (6.48±0.83) d, (21.88±1.78) d vs. (24.44±2.44) d, respectively. The differences were statistically significant(t=17.919, 17.881, 14.978, 15.532, and 4.745; all P values<0.05). No significant differences were observed in the incidence of perioperative complications and mortality between the two groups (all P values>0.05). All patients were followed up for 1 year. No serious complications were observed, except for two cases of slight type-Ⅱ internal leakage in the EVAR group.Conclusions Open surgery and endovascular surgery for abdominal aortic aneurysm achieve good short-term treatment results. Compared with open surgery, endovascular repair has shorter operation time, less intraoperative bleeding, shorter fasting, shorter bed rest and hospital stay, and faster postoperative recovery.
徐超, 余朝文, 任天才, 陈世远, 孙勇, 高涌. 腹主动脉瘤开放手术和腔内手术治疗的近期疗效分析[J]. 中华解剖与临床杂志, 2021, 26(6): 658-662.
Xu Chao, Yu Chaowen, Ren Tiancai, Chen Shiyuan, Sun Yong, Gao Yong. Early efficacy of open surgery and endovascular surgery for abdominal aortic aneurysm. Chinese Journal of Anatomy and Clinics, 2021, 26(6): 658-662.
Kent KC, Zwolak RM, Egorova NN, et al. Analysis of risk factors for abdominal aortic aneurysm in a cohort of more than 3 million individuals[J]. J Vasc Surg, 2010, 52(3): 539-548. DOI:10.1016/j.jvs.2010.05.090.
[2]
Jacob AD, Barkley PL, Broadbent KC, et al. Abdominal aortic aneurysm screening[J]. Semin Roentgenol, 2015, 50(2): 118-126. DOI:10.1053/j.ro.2014.10.003.
[3]
Torres-Fonseca M, Galan M, Martinez-Lopez D, et al. Pathophisiology of abdominal aortic aneurysm: biomarkers and novel therapeutic targets[J]. Clin Investig Arterioscler, 2019, 31(4): 166-177. DOI:10.1016/j.arteri.2018.10.002.
[4]
Shreibati JB, Baker LC, Hlatky MA, et al. Impact of the screening abdominal aortic aneurysms very efficiently (SAAAVE) act on abdominal ultrasonography use among medicare beneficiaries[J]. Arch Intern Med, 2012,172(19): 1456-1462. DOI:10.1001/archinternmed.2012.4268.
[5]
Heikkinen M, Salenius JP, Auvinen O. Ruptured abdominal aortic aneurysm in a well-defined geographic area[J]. J Vasc Surg, 2002, 36(2): 291-296. DOI:10.1067/mva.2002.125479.
[6]
Rosenblum JM, Chen EP. Thoracoabdominal aortic aneurysm repair: open, endovascular, or hybrid?[J]. Gen Thorac Cardiovasc Surg, 2019, 67(1): 175-179. DOI:10.1007/s11748-017-0820-y.
[7]
Kobeissi E, Hibino M, Pan H, et al. Blood pressure, hypertension and the risk of abdominal aortic aneurysms: a systematic review and meta-analysis of cohort studies[J]. Eur J Epidemiol, 2019, 34(6): 547-555. DOI:10.1007/s10654-019-00510-9.
[8]
Altobelli E, Rapacchietta L, Profeta VF, et al. Risk factors for abdominal aortic aneurysm in population-based studies: a systematic review and meta-analysis[J]. Int J Environ Res Public Health, 2018, 15(12) DOI:10.3390/ijerph15122805.
[9]
Rapsomaniki E, Timmis A, George J, et al. Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1.25 million people[J]. Lancet, 2014, 383(9932): 1899-1911. DOI:10.1016/S0140-6736(14)60685-1.
[10]
Maegdefessel L, Azuma J, Toh R, et al. MicroRNA-21 blocks abdominal aortic aneurysm development and nicotine-augmented expansion[J]. Sci Transl Med, 2012, 4(122): 122ra22. DOI:10.1126/scitranslmed.3003441.
[11]
Schmitz-Rixen T, Keese M, Hakimi M, et al. Ruptured abdominal aortic aneurysm-epidemiology, predisposing factors, and biology[J]. Langenbecks Arch Surg, 2016, 401(3): 275-288. DOI:10.1007/s00423-016-1401-8.
[12]
Villard C, Hultgren R. Abdominal aortic aneurysm: sex differences[J]. Maturitas, 2018, 109: 63-69. DOI:10.1016/j.maturitas.2017.12.012.
Saucy F, Déglise S, Holzer T, et al. Abdominal aortic aneurysm: what about screening?[J]. Curr Pharm Des, 2015, 21(28): 4084-4087. DOI:10.2174/1381612821666150826095148.
[15]
Guirguis-Blake JM, Beil TL, Senger CA, et al. Ultrasonography screening for abdominal aortic aneurysms: a systematic evidence review for the U.S. Preventive Services Task Force[J]. Ann Intern Med, 2014, 160(5): 321-329. DOI:10.7326/M13-1844.
[16]
Gallitto E, Faggioli G, Mascoli C, et al. Long-term efficacy of EVAR in patients aged less than 65 years with an infrarenal abdominal aortic aneurysm and favorable anatomy[J]. Ann Vasc Surg, 2020, 67: 283-292. DOI:10.1016/j.avsg.2020.03.038.
[17]
Shi F, He Y, Wang S, et al. Endovascular and open surgical repair of abdominal aortic aneurysms: a comparative analysis of western and Chinese studies[J]. Rev Cardiovasc Med, 2020, 21(1): 75-92. DOI:10.31083/j.rcm.2020.01.513.
[18]
Yokoyama Y, Kuno T, Takagi H. Meta-analysis of phase-specific survival after elective endovascular versus surgical repair of abdominal aortic aneurysm from randomized controlled trials and propensity score-matched studies[J]. J Vasc Surg, 2020, 72(4): 1464-1472.e6. DOI:10.1016/j.jvs.2020.03.041.
[19]
Li B, Khan S, Salata K, et al. A systematic review and meta-analysis of the long-term outcomes of endovascular versus open repair of abdominal aortic aneurysm[J]. J Vasc Surg, 2019, 70(3): 954-969.e30. DOI:10.1016/j.jvs.2019.01.076.
[20]
de Guerre L, Dansey K, Li C, et al. Late outcomes after endovascular and open repair of large abdominal aortic aneurysms[J]. J Vasc Surg, 2021, 74(4): 1152-1160. DOI:10.1016/j.jvs.2021.02.024.
[21]
Stather PW, Sidloff DA, Rhema IA, et al. A review of current reporting of abdominal aortic aneurysm mortality and prevalence in the literature[J]. Eur J Vasc Endovasc Surg, 2014, 47(3): 240-242. DOI:10.1016/j.ejvs.2013.11.007.