腺泡状软组织肉瘤的CT及MRI影像特征

doi:10.3760/cma.j.cn101202-20230626-00165

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摘要目的探讨腺泡状软组织肉瘤（ASPS）的CT及MRI影像特征。方法横断面研究。回顾性分析西安交通大学第一附属医院2012年1月—2022年1月经手术病理确诊的11例ASPS患者的影像学资料，其中男4例、女7例，首次就诊年龄20~52（30.5±13.2）岁。术前5例患者行CT平扫检查，1例行CT及MR平扫，5例行MR平扫（其中1例同时行MR增强扫描）。基于患者的CT及MRI的影像学表现，观察肿瘤位置、形状、大小、边界、CT 密度、MRI信号特点等影像学特征。结果 11例ASPS患者中，肿瘤位于左侧股直肌4例、左侧股中间肌1例、右侧股中间肌1例、右侧股骨四头肌1例、左上肢三角肌1例、左侧腹膜后3例；9例呈卵圆形，1例呈圆形，1例呈不规则形；肿瘤最大直径4.7~11.1（9.1±2.3） cm；9例病灶边界清晰，2例病灶上下缘边界不清。CT影像特征：6例病灶呈不均匀稍低密度，CT值为26~38（35.0±4.3）HU，1例病灶内见点状钙化。MRI特征：MR平扫T1加权像（T₁WI）2例病灶呈等信号，4例呈稍高信号；6例T₂WI呈不均匀高信号，病灶内及周围均见低信号的流空血管影；1例MR增强扫描呈明显不均匀强化。结论 ASPS好发于四肢肌肉。其CT表现为不均匀的低密度影；MRI征象有一定的特异性，T1WI呈等或稍高信号，T2WI呈不均匀高信号，病灶内及周围有低信号的流空血管影，增强扫描呈明显强化。熟悉ASPS的CT及MRI影像特征有助于对患者的诊断和治疗。

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	吴珊
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关键词 ：软组织肿瘤, 腺泡状软组织肉瘤, 磁共振成像, 计算机体层成像, 影像学特征

Abstract：Objective This study aimed to investigate CT and MR imaging features of alveolar soft part sarcoma (ASPS) were investigated. Methods This was a cross-sectional study. The imaging data of 11 patients with ASPS confirmed by surgery and pathology in the First Affiliated Hospital of Xi'an Jiaotong University from January 2012 to January 2022 were retrospectively analyzed. The patients included four males and seven females, aged 20-52 (30.5±13.2) years. Among them, five patients underwent CT scan, five patients underwent MR scan (including one case scanned by enhanced MR at the same time), and one patient underwent CT and MR scans. The CT and MRI imaging features of ASPS such as the tumor location, shape, size, boundary, CT value, MR image signal characteristic and soon were summarized. Results The tumors were located in the left rectus femoris in four cases, left vastus intermedius in one case, right vastus intermedius in one case, right quadriceps femoris in one case, left upper extremity deltoid in one case, and left retroperitoneum in three cases. Nine cases were oval, one case was round, and one case was irregular. The maximum diameter of the tumor ranged from 4.7-11.1 (9.1±2.3) cm. The boundaries of the lesions were clear in nine cases, and the upper and lower edges of the lesions were unclear in two cases. The CT imaging features showed slightly low and uneven densities in six lesions, and the average CT value was 26-38 (35.0±4.3) HU. Punctate calcification was found in one lesion. As for the MRI imaging features, the T₁WI MRI scan showed isointensity in two cases and slightly hyperintensity in four cases and uneven hyperintense in six cases. All showed cases shoed low signal empty vascular shadows in and around the lesions. The contrast-enhanced MRI of one case showed obvious and uneven enhancement. Conclusion ASPS is more common in the muscles of the limbs. CT shows uneven low density, and MRI shows specific signs: equal signal or slightly hyperintensity on T1WI, uneven hyperintensity on T₂WI, low signal empty vascular shadows in and around the lesions, and obvious enhancement on enhanced MRI. Familiarity with the CT and MRI imaging features of ASPS can help radiologists and clinicians to diagnose and operate.

Key words： Soft tissue neoplasms Alveolar soft part sarcoma Magnetic resonance imaging Computer tomography Imaging characteristic

收稿日期: 2023-06-26

通讯作者: 徐小玲，Email：yxxl0813@163.com

引用本文:

吴珊, 刘军, 张明, 徐小玲. 腺泡状软组织肉瘤的CT及MRI影像特征[J]. 中华解剖与临床杂志, 2024, 29(3): 148-152.
Wu Shan, Liu Jun, Zhang Ming, Xu Xiaoling. CT and MR imaging characteristic of alveolar soft tissue sarcoma. Chinese Journal of Anatomy and Clinics, 2024, 29(3): 148-152.

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http://www.cjac.com.cn/CN/10.3760/cma.j.cn101202-20230626-00165 或 http://www.cjac.com.cn/CN/Y2024/V29/I3/148

[1]	Viry F, Orbach D, Klijanienko J, et al. Alveolar soft part sarcoma-radiologic patterns in children and adolescents[J]. Pediatr Radiol, 2013, 43(9): 1174-1181. DOI: 10.1007/s00247-013-2667-4.
[2]	高慧,韩雷,郭晓丽,等.腺泡状软组织肉瘤的磁共振成像表现及临床病理学分析[J].肿瘤影像学, 2019, 28(5): 315-318. DOI: 10.19732/j.cnki.2096-6210.2019.05.005.
	Gao H, Han L, Guo XL, et al. Magnetic resonance imaging findings and clinicopathologic features of alveolar soft-part sarcoma[J]. Oncoradiology, 2019, 28(5): 315-318. DOI: 10.19732/j.cnki.2096-6210.2019.05.005.
[3]	李培岭,翟昭华,王萍,等.腺泡状软组织肉瘤的影像学表现[J]. 实用放射学杂志, 2013, 29(1): 158-160.
	Li PL, Zhai ZH, Wang P, et al. Imaging findings of alveolar soft tissue sarcoma[J]. J Pract Radiol, 2013, 29(1): 158-160.
[4]	Sood S, Baheti AD, Shinagare AB, et al. Imaging features of primary and metastatic alveolar soft part sarcoma: single institute experience in 25 patients[J]. Br J Radiol, 2014, 87(1036): 20130719. DOI: 10.1259/bjr.20130719.
[5]	Crombé A, Brisse HJ, Ledoux P, et al. Alveolar soft-part sarcoma: can MRI help discriminating from other soft-tissue tumors? A study of the French sarcoma group[J]. Eur Radiol, 2019,29(6):3170-3182. DOI: 10.1007/s00330-018-5903-3.
[6]	Gulati M, Mittal A, Barwad A, et al. Imaging and pathological features of alveolar soft part sarcoma: analysis of 16 patients[J]. Indian J Radiol Imaging, 2021,31(3):573-581. DOI: 10.1055/s-0041-1735501.
[7]	Singh N, Gupta P, Misra S, et al. Alveolar soft part sarcoma: a case report and review of the literature[J]. Cytopathology, 2022, 33(5): 622-627. DOI: 10.1111/cyt.13134.
[8]	Satyam, Manchanda A, Ramya K, et al. Alveolar soft part sarcoma of the retroperitoneum: a case report[J]. J Radiol Case Rep, 2021,15(10): 20-26. DOI: 10.3941/jrcr.v15i10.4003.
[9]	Li X, Ye Z. Magnetic resonance imaging features of alveolar soft part sarcoma: report of 14 cases[J]. World J Surg Oncol, 2014,12:36. DOI: 10.1186/1477-7819-12-36.
[10]	Portera CA, Ho V, Patel SR, et al. Alveolar soft part sarcoma: clinical course and patterns of metastasis in 70 patients treated at a single institution[J]. Cancer, 2001,91(3):585-591. DOI: 10.1002/1097-0142(20010201)91:33.0.co;2-0.
[11]	程静,涂频,王建军,等.腺泡状软组织肉瘤48例临床病理分析[J].中华病理学杂志, 2016, 45(1): 16-20. DOI: 10.3760/cma.j.issn.0529-5807.2016.01.005.
	Cheng J, Tu P, Wang JJ, et al. Alveolar soft part sarcoma: a clinicopathologic analysis of 48 cases[J]. Chin J Pathol, 2016, 45(1): 16-20. DOI: 10.3760/cma.j.issn.0529-5807.2016.01.005.
[12]	吕长磊,王凯, 李剑锋,等.下肢腺泡状软组织肉瘤的影像学表现[J].实用放射学杂志,2018, 34(9): 1414-1417. DOI: 10.3969/j.issn.1002-1671.2018.09.026.
	Lyu CL, Wang K, Li JF, et al. Imaging features of alveolar soft part sarcoma of the lower extremities[J]. J Pract Radiol, 2018, 34(9):1414-1417. DOI: 10.3969/j.issn.1002-1671.2018.09.026.
[13]	周建功, 马小龙, 汪建华, 等. 腺泡状软组织肉瘤的影像学特征与病理对照[J].中华放射学杂志,2013,47(2):162-165. DOI: 10.3760/cma.j.issn.1005-1201.2013.02.014.
	Zhou JG, Ma XL, Wang JH, et al.Imaging features and pathological findings of alveolar soft part sarcoma[J].Chin J Radiol,2013,47(2):162-165. DOI: 10.3760/cma.j.issn.1005-1201.2013.02.014.
[14]	李彩霞,徐焱,赵福香.四肢腺泡状软组织肉瘤MRI诊断[J].临床放射学杂志, 2016, 35(11): 1730-1734. DOI: 10.13437/j.cnki.jcr.2016.11.025.
	Li CX, Xu Y, Zhao FX. MRI diagnosis of alveolar soft part sarcoma[J]. Journal of Clinical Radiology, 2016, 35(11): 1730-1734. DOI: 10.13437/j.cnki.jcr.2016.11.025.
[15]	罗芙蓉,詹阿来,黄庆文.腺泡状软组织肉瘤三例磁共振成像表现与文献复习[J].实用医学影像杂志, 2019,20(1)41-43. DOI: 10.16106/j.cnki.cn14-1281/r.2019.01.013.
	Luo FR, Zhan AL, Huang QW. MRI findings of 3 cases with alveolar soft-part sarcoma and literature review[J]. Journal of Practical Medical Imaging,2019, 20(1): 41-43. DOI: 10.16106/j.cnki.cn14-1281/r.2019.01.013.
[16]	Qiao PF, Shen LH, Gao Y, et al. Alveolar soft part sarcoma: clinicopathological analysis and imaging results[J]. Oncol Lett, 2015,10(5): 2777-2780. DOI: 10.3892/ol.2015.3694.
[17]	Pennacchioli E, Fiore M, Collini P, et al. Alveolar soft part sarcoma: clinical presentation, treatment, and outcome in a series of 33 patients at a single institution[J]. Ann Surg Oncol, 2010,17(12): 3229-3233. DOI: 10.1245/s10434-010-1186-x.