Clinical efficacy of anterior minimally invasive plate osteosynthesis in the surgical treatment of adult mid-distal humeral diaphyseal fractures
Wang Lijun1, Qian Minglei1, Wu Jian1, Fan Shengli1, Tang Tiansi2
1Department of Orthopedics, Affiliated Changshu Hospital of Nantong University, Changshu 215500, China; 2Department of Orthopedics, the First Affiliated Hospital of Soochow University, Suzhou 215006, China
Abstract:Objective This study aimed to explore the clinical outcomes of anterior minimally invasive plate osteosynthesis (MIPO) in the surgical treatment of adult mid-distal humeral diaphyseal fractures. Methods A retrospective cohort study was conducted to analyze 73 patients with adult mid-distal humeral diaphyseal fractures admitted to the Affiliated Changshu Hospital of Nantong University from October 2016 to September 2022. The patients consisted of 42 males and 31 females, aged 18-86 (53.0±20.4) years. They were divided into the MIPO group (n=39) and the anterolateral approach open reduction and internal fixation (ORIF) group (n=34) in accordance with the surgical procedure used. Baseline data, such as gender, age, cause of injury, duration of disease, and fracture AO classification, were compared between the MIPO and ORIF groups. Operative time, scar length, radiation exposure time, intraoperative blood loss, postoperative hospitalization time, bone healing time, and surgical-related complications were recorded and analyzed. The functional status of the shoulder and elbow was evaluated using the American Shoulder and Elbow Surgery (ASES) scoring system at different time points (1 week, 1 month, 3 months, and 1 year after the operation) between the MIPO and ORIF groups. Results All the operations in both groups were successfully performed, and the patients were followed up for 13-48 (29.6±2.3) months. No significant difference was observed in the basic data, such as age, gender, cause of injury, duration of disease, and fracture AO classification between the MIPO and ORIF groups (all P values >0.05). No significant difference was noted in surgical time, radiation exposure time, and bone healing time between the two groups (all P values >0.05). Compared with that in the ORIF group, incision length in the MIPO group was shorter ([8.4±1.1] cm versus [13.8±1.9] cm), intraoperative blood loss was less (138.0 [132.0,167.0] mL versus 248.5 [240.8, 290.3] mL), postoperative hospital stay was shorter (4.0 [3.0, 4.0] days versus 6.0 [5.0, 7.0] days), and the differences were statistically significant (t=-14.37, Z=-7.33, Z=-6.29; all P values <0.05). The ASES scores of the MIPO group were higher than those of the ORIF group at 1 week, 1 month, and 3 months after surgery, and the differences were statistically significant (t=6.50, 4.62, 4.67; all P values <0.05). However, no significant difference in ASES scores was observed between the two groups 1 year after surgery (P >0.05). Three cases experienced numbness on the anterolateral forearm because of an injury to the lateral antebrachial cutaneous nerve. Furthermore, neither infection nor iatrogenic radial nerve palsy was observed in the MIPO group. In the ORIF group, four cases exhibited delayed union and one case suffered from infected nonunion after primary surgical stabilization. All these patients were uneventfully healed with revision surgery of autogenous iliac bone grafting. Seven cases experienced numbness between the thumb and the index finger due to radial nerve injury, and they recovered uneventfully 3 months later. Conclusion The MIPO technique via the anterior approach avoids the need for radial nerve visualization and extensive soft tissue dissection. It contributes to less disruption of the blood supply at the segment level and satisfactory clinical outcome. Therefore, this technique should be considered an attractive alternative for patients who require operative intervention of adult mid-distal humeral diaphyseal fractures.
刘磊, 孙家元, 杨宗酉, 等. 2003年至2012年河北医科大学第三医院成人肱骨干骨折的流行病学分析[J].中华创伤骨科杂志,2015,17(1):71-74. DOI: 10.3760/cma.j.issn.1671-7600.2015.01.017.Liu L, Sun JY, Yang ZX, et al.Epidemiological analysis of adult humeral shaft fractures in the Third Affiliated Hospital to Hebei Medical University from 2003 through 2012[J]. Chin J Orthop Trauma,2015,17(1):71-74. DOI: 10.3760/cma.j.issn.1671-7600.2015.01.017
[2]
Gallusser N, Barimani B, Vauclair F.Humeral shaft fractures[J]. EFORT Open Rev, 2021,6(1):24-34. DOI: 10.1302/2058-5241.6.200033
[3]
Apivatthakakul T, Arpornehayanon O, Bavornratanavech S.Minimally invasive plate osteosynthesis(MIPO)of the humeral shaft fracture. Is it possible? A cadaveric study and preliminary report[J]. Injury, 2005.36:530-538. DOI: 10.1016/j.injury.2004.05.006
[4]
汪李军, 史源欣, 邵伟忠, 等. 肱骨远端关节外解剖锁定加压钢板内固定治疗肱骨干中下段骨折[J].中华创伤骨科杂志,2017,19(10):907-910. DOI: 10.3760/cma.j.issn.1671-7600.2017.10.014.Wang LJ, Shi YX, Shao WZ, et al.Osteosynthesis of mid-distal humeral diaphyseal fracture with an anatomically precontoured extra-articular distal plate system[J].Chin J Orthop Trauma,2017,19(10):907-910. DOI: 10.3760/cma.j.issn.1671-7600.2017.10.014
[5]
Hosseini Khameneh SM, Abbasian M, Abrishamkarzadeh H, et al.Humeral shaft fracture: a randomized controlled trial of nonoperative versus operative management (plate fixation)[J]. Orthop Res Rev, 2019,11:141-147. DOI: 10.2147/ORR.S212998
[6]
Pollock FH, Maurer JP, Sop A, et al.Humeral shaft fracture healing rates in older patients[J]. Orthopedics, 2020,43(3):168-172. DOI: 10.3928/01477447-20200213-03
[7]
Serrano R, Mir HR, Sagi HC, et al.Modern results of functional bracing of humeral shaft fractures: a multicenter retrospective analysis[J]. J Orthop Trauma, 2020,34(4):206-209. DOI: 10.1097/BOT.0000000000001666
[8]
Yiğit Ş.What should be the timing of surgical treatment of humeral shaft fractures?[J]. Medicine (Baltimore), 2020,99(17):e19858. DOI: 10.1097/MD.0000000000019858
[9]
Colello MJ, Hunter MD, Tanner SL, et al.Intramedullary nail fixation for the treatment of pathologic humeral shaft fractures[J]. Orthopedics, 2020,43(5):e389-e398. DOI: 10.3928/01477447-20200619-08
[10]
刘超, 刘建峰, 李丹. 锁定加压钢板 、交锁髓内钉与可膨胀髓内钉治疗方案对肱骨干骨折的中远期疗效比较[J].创伤外科杂志,2019,21(6):425-430. DOI: 10.3969/j.issn.1009-4237.2019.06.006.Liu C, Liu JF, Li D.Comparison of mid-long term effect of LCP, IMN and EIMN for humeral shaft fracture[J]. Journal of Traumatic Surgery,2019,21(6):425-430. DOI: 10.3969/j.issn.1009-4237.2019.06.006
[11]
孙卫强, 于大鹏, 徐立民. 微创逆行弹性钉髓内三维角度面性支撑治疗成人肱骨干骨折的疗效观察[J].中华手外科杂志,2022,38(4):271-273. DOI: 10.3760/cma.j.cn311653-20210725-00238.Sun WQ, Yu DP, Xu LM.Observation on the clinical efficacy of minimally invasive retrograde elastic nail intramedullary three-dimensional angle plane support in the treatment of humeral shaft fractures in adults[J].Chin J Hand Surg,2022,38(4):271-273. DOI: 10.3760/cma.j.cn311653-20210725-00238
[12]
任东, 邢丹谋, 张明, 等. 桥接组合内固定系统与锁定钉板系统治疗闭合性肱骨干骨折的疗效比较[J].中华骨科杂志,2022,42(3):156-163. DOI: 10.3760/cma.j.cn121113-20211018-00600.Ren D, Xin DM, Zhang M, et al.Bridge combined internal fixation system and locking plate system in treatment of closed humeral shaft fracture[J]. Chin J Orthop,2022,42(3):156-163. DOI: 10.3760/cma.j.cn121113-20211018-00600
Colombi R, Chauvet T, Labattut L, et al.Is distal locking screw necessary for intramedullary nailing in the treatment of humeral shaft fractures? A comparative cohort study[J]. Int Orthop, 2019,43(9):2151-2160. DOI: 10.1007/s00264-018-4091-8
[15]
安智全, 曾炳芳, 王烨明, 等. 用MIPO技术治疗肱骨干中下段骨折的解剖及初步临床报告[J].中华手外科杂志,2006,22(6):336-338. DOI: 10.3760/cma.j.issn.1005-054X.2006.06.006.An ZQ, Zeng BF, Wang YM, et al.Treatment of mid-distal humeral shaft fractures using minimally invasive plating osteosynthesis (MIPO) technique: anatomical considerations and preliminary clinical results[J]. Chin J Hand Surg, 2006, 22(6): 336-338. DOI: 10.3760/cma.j.issn.1005-054X.2006.06.006
[16]
Davies G, Yeo G, Meta M, et al.Case-Match Controlled comparison of minimally invasive plate osteosynthesis and intramedullary nailing for the stabilization of humeral shaft fractures[J]. J Orthop Trauma, 2016,30(11):612-617. DOI: 10.1097/BOT.0000000000000643
[17]
Hohmann E, Glatt V, Tetsworth K.Minimally invasive plating versus either open reduction and plate fixation or intramedullary nailing of humeral shaft fractures: a systematic review and meta-analysis of randomized controlled trials[J]. J Shoulder Elbow Surg, 2016,25(10):1634-1642. DOI: 10.1016/j.jse.2016.05.014
[18]
张培训, 付中国, 王依林, 等. 应用MIPPO技术前侧入路预旋转塑形锁定板钉治疗肱骨干中段B型、C型骨折[J].中华肩肘外科电子杂志,2017,5(1):3-8. DOI: 10.3877/cma.j.issn.2095-5790.2017.01.002.Zhang PX, Fu ZG, Wang YL, et al.Treatment of humeral shaft fracture (Type B, C) with pre-rotating moulding locking plate by anterior approach MIPPO technique[J].Chin J Shoulder Elbow(Electronic Edition),2017,5(1):3-8. DOI: 10.3877/cma.j.issn.2095-5790.2017.01.002
[19]
汤艳, 黄立新, 徐杰. 上臂前正中切口前侧入路切开复位接骨板内固定术治疗肱骨干骨折16例[J].中华解剖与临床杂志,2014,19(1):64-66. DOI: 10.3760/cma.j.issn.2095-7041.2014.01.017Tang Y, Huang LX, Xu J.Before the upper arm midline incision into the path of the side bone plate internal fixation (orif) clinical observation on 16 cases of humeral fractures[J]. Chin J Anat Clin,2014,19(1):64-66. DOI: 10.3760/cma.j.issn.2095-7041.2014.01.017
[20]
陈韬予, 韩鹏飞, 李鹏翠, 等. 微创经皮接骨板与切开复位钢板内固定治疗肱骨干骨折疗效的Meta分析[J].中华创伤骨科杂志,2019,21(5):416-421. DOI: 10.3760/cma.j.issn.1671-7600.2019.05.010.Chen TY, Han PF, Li PC, et al.Minimally invasive plate osteosynthesis versus open reduction and internal fixation for humeral shaft fractures: a Meta-analysis[J].Chin J Orthop Trauma,2019,21(5):416-421. DOI: 10.3760/cma.j.issn.1671-7600.2019.05.010
[21]
任东,邢丹谋,肖志宏,等. 经皮微创钢板固定治疗肱骨干骨折的疗效分析[J]. 中华肩肘外科电子杂志,2019,7(4):329-334. DOI :10.3877/cma.j.issn.2095-5790.2019.04.007.Ren D, Xing DM, Xiao ZH, et al.Clinical outcome analysis of minimally invasive percutaneous plate fixation for treatment of humeral shaft fractur[J]. Chin J Shoulder Elbow(Electronic Edition), 2019,7(4):329-334. DOI: 10.3877/cma.j.issn.2095-5790.2019.04.007
[22]
Hendy BA, Zmistowski B, Wells Z, et al.Humeral shaft fractures: surgical versus nonsurgical management in workers' compensation[J]. Arch Bone Jt Surg, 2020,8(6):668-674. DOI: 10.22038/abjs.2020.44301.2211
Tetsworth K, Hohmann E, Glatt V.Minimally invasive plate osteosynthesis of humeral shaft fracture: current state of the art[J]. J Am Acad Orthop Surg, 2018, 26(18):652-661. DOI: 10.5435/JAAOS-D-17-00238
[25]
吴松柏, 谭伦, 钟永平, 等. 外固定架辅助下微创经皮钢板内固定治疗肱骨干骨折[J].临床骨科杂志,2020,23(2):233-235. DOI: 10.3969/j.issn.1008-0287.2020.02.028.Wang SB, Tan L, Zhong YP, et al.Treatment of humeral shaft fracture with minimally invasive percutaneous plate osteosynthe- sis assisted by external fixator[J]. Journal of Clinical Orthopaedics,2020,23(2):233-235. DOI: 10.3969/j.issn.1008-0287.2020.02.028
[26]
张晓娟, 李升, 吴卫卫, 等. 人体肱骨干显微骨硬度分布特征的实验研究[J].中华解剖与临床杂志,2019,24(4):318-321. DOI: 10.3760/cma.j.issn.2095-7041.2019.04.002.Zhang XJ, Li S, Wu WW, et al.Micro-hardness distribution of humeral shaft in human skeleton[J].Chin J Anat Clin, 2019,24(4):318-321. DOI: 10.3760/cma.j.issn.2095-7041.2019.04.002
[27]
刘洪波, 张伯松, 贺良, 等. 肱骨干骨折合并桡神经损伤一期桡神经探查与保守治疗的疗效比较[J].中华创伤骨科杂志,2010,12(9):801-804. DOI: 10.3760/cma.j.issn.1671-7600.2010.09.001.Liu HB, Zhang BS, He L, et al.Early nerve exploration vs. Conservative observation in clinical management of radial nerve palsy associated with humeral shaft fracture[J]. Chin J Orthop Trauma,2010,12(9):801-804. DOI: 10.3760/cma.j.issn.1671-7600.2010.09.001
[28]
Belayneh R, Lott A, Haglin J, et al.Final outcomes of radial nerve palsy associated with humeral shaft fracture and nonunion[J]. J Orthop Traumatol, 2019,20(1):18. DOI: 10.1186/s10195-019-0526-2.