Abstract：Objective To explore the clinical results of new design stagewise double-saccule (NDSDS) for treatment of osteoporotic vertebral compression fracture(OVCF) of thoracolumbar.Methods This was a prospective, single-center, randomized clinical trial. Forty patients (108 vertebral) with OVCF of thoracolumbar were managed from January 2011 to June 2013 in the 184th Hospital of PLA, and were randomly divided into two groups. Observation group: 20 patients (53 vertebral) were treated by NDSDS. Control group: 20 patients (55 vertebral) were treated by traditional saccule. Cobb angle, visual analogue scale (VAS) and Oswestry disability index (ODI) were observed, and the operative time of single-vertebral was recorded.Results All patients were followed up 6-24 months, average(14±3.4)months. Observation group: The preoperative Cobb angle was 56.05°±9.58° , the difference was 29.25°±4.84° 1 week after operation and 26.80°±4.65° 24 weeks after operation. Preoperative VAS was 7.80±0.62, the difference was 5.10±1.21 1 week after operation and 5.35±1.13 24 weeks after operation. Preoperative ODI was 76.9±3.34, the difference was 54.5±10.58 1 week after operation and 52.7±5.82 24 weeks after operation. Control group: Preoperative Cobb angle was 57.05°±10.49°, the difference was 31.00°±6.91° 1 week after operation and 28.75°±6.77° 24 weeks after operation, preoperative VAS was 7.97±0.76 , the difference was 5.20±1.24 1 week after operation and 5.50±1.14 24 weeks after operation, preoperative ODI was 79.7±4.17, the difference was 62.6±5.03 1 week after operation and 58.6±5.58 24 weeks after operation. All index above had no significant difference interclass (all P values>0.05), and had significantly difference in group before and after operation (all P values<0.05). The observation group operative time of single-vertebral was (15.04±5.03) min and the control group was (20.39±10.09) min (P<0.05).Conclusions It is a simple, safe and efficient way to treat patients with OVCF by using NDSDS, which has little trauma and low pain.
赵敏，周江军，罗飞，刘达，吕仁发，杨俊，史柏娜，付美清，肖春林，雷雪，余专一，程球新. 新型分段式双球囊撑开器治疗多节段骨质疏松性胸腰椎压缩性骨折的病例对照研究[J]. 中华解剖与临床杂志, 2015, 20(5): 390-394.
Zhao Min, Zhou Jiangjun, Luo Fei, Liu Da, Lyu Renfa, Yang Jun, Shi Bona, Fu Meiqing, Xiao Chunlin, Lei Xue, Yu Zhuanyi, Cheng Qiuxin. Treatment of multsegments osteoporotic vertebral compression fracture by new design stagewise double-saccule: a case-control study. Chinese Journal of Anatomy and Clinics, 2015, 20(5): 390-394.
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