Correlation between the semiquantitative evaluations of susceptibility-weighted imaging and dynamic susceptibility-weighted contrast-enhanced perfusion-weighted magnetic resonance imaging in patients with astrocytic tumor
Liu Li*, Han Tong, Zhang Yunting, Lei Jing, Guo Jun, Liu Hui
*Department of Radiology, Tianjin Huanhu Hospital, Tianjin Cerebral Vascular and Neural Degenerative Disorder Key Laboratory, Tianjin 300060, China
Abstract：Objective Toevaluate the correlations between the indexes of susceptibility-weighted imaging(SWI) and those of perfusion-weighted magnetic resonance imaging(PI) in astrocytic tumors before the operation.Methods Ninety-eight patients were performed conventional, contrast MR scan, SWI and PI scan by Siemens 3.0T magnetic resonance imaging system. Intratumor susceptibility hypo-intensity area (ITSHIA) in SWI was observed and semiquantitative data were acquired. Maximum relative rCBV values of solid part within the tumor (rrCBVintramax) and surrounding area of tumor (rrCBVperimax) acquired by PI were calculated. Comparison of the rrCBVintramax and rrCBVperimax in astrocytic tumor of different grade were conducted. The corresponding situation between hot spot of PI and ITSHIA were evaluated and correlation between SWI and PI were compared.Results rrCBVintramax (rs=0.662,P<0.01) of astrocytic tumors was related positively linearly with pathological grade. rrCBVperimax (rs=0.794,P<0.01) was also markedly related. The rrCBVintramax of pilocytic astrocytoma was higher than that of astrocytoma(Ⅱ),which was similar to that of grade Ⅲ, whereas rrCBVperimax showed no differences compared with astrocytoma(Ⅱ) and markedly lower than the tumor of high grade. The semiquantitative data of ITSHIA had a typical positive correlation with rrCBVintramax and rrCBVperimax respectively. The area including hot spots in PI was not to be able completely correspondent with ITSHIA.Conclusions Semiquantitative indexes of SWI are closely related to that of PI. Both PI and SWI may be used as sensitive indexes of evaluating pathological grade of astrocytic tumor. The incompletely correspondent between hot spot and ITSHIA may be due to an association with different machismos of PI and SWI.
刘力, 韩彤, 张云亭, 雷静, 郭军, 刘卉. 星形细胞肿瘤磁敏感成像与动态对比剂MR灌注加权成像的相关性研究[J]. 中华解剖与临床杂志, 2015, 20(1): 19-26.
Liu Li, Han Tong, Zhang Yunting, Lei Jing, Guo Jun, Liu Hui. Correlation between the semiquantitative evaluations of susceptibility-weighted imaging and dynamic susceptibility-weighted contrast-enhanced perfusion-weighted magnetic resonance imaging in patients with astrocytic tumor. Chinese Journal of Anatomy and Clinics, 2015, 20(1): 19-26.
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2015, Vol. 20 
