Abstract:Objective To study the morphologic characteristics and classification of the cavum septum pellucidum (CSP) and the cavum vergae (CV) by MR scanning, as an aid for optimizing surgical approaches.Methods From January to April 2019, 200 patients with conventional 5.0 mm thick cranial MR scans were enrolled at Renji Hospital, School of Medicine, Shanghai Jiaotong University. The incidence of CSP was observed and its morphological characteristics were studied. Furthermore, thin-layer MRI scanning with 1.0-2.0 mm slices was performed in 75 patients diagnosed with drug-resistant epilepsy admitted to presurgical evaluation from March 2018 to March 2019. After image fusion and three-dimensional reconstruction, the maximum diameter of length, width and height of CSP was measured in horizontal and coronal images, and the average value was calculated.Results CSP was presented on conventional MR scans in 189 of 200 patients (94.5%), suggested that most patients had visible CSP. CSP was usually displayed at the level of the foramen of Monro and at the lowest level of the body of the lateral ventricles, which located just posterior to the genu of the corpus callosum and anterosuperior to the columns of the fornix. An imaging classification of CSP had been developed: close (typeⅠ), gap (typeⅡ), dilation (typeⅢ), cyst (type Ⅳ)and variations (typeⅤ), accounts for 4.5%(9/200)、91.5%(183/200)、1.5%(3/200)、1.5%(3/200) and 1.0%(2/200) of cases in this series, respectively. Two types of CV were identified according to imaging: isolated occurrence or communicating with CSP, accounts for 1.0%(2/200) and 1.5%(3/200) of cases, respectively. For the most common clinical type of CSP (typeⅡ), the average transverse, vertical, and longitudinal dimensions for CSP were 2.3 mm, 1.5 mm, and 3.6 mm, respectively.Conclusions CSP shows different shapes and sizes on MRIs. Preoperative MRI assessment of the presence of CSP and its morphological features can be used as an important reference index the CSP separation and the selection of surgical approach.
周洪语, 叶晓来, 马军峰, 刘强强, 王昌泉, 徐纪文. 透明隔间腔的MR影像解剖学研究[J]. 中华解剖与临床杂志, 2020, 25(2): 123-128.
Zhou Hongyu, Ye Xiaolai, Ma Junfeng, Liu Qiangqiang, Wang Changquan, Xu Jiwen. MR imaging and anatomical study of cavum septum pellucidum et vergae. Chinese Journal of Anatomy and Clinics, 2020, 25(2): 123-128.
Shaw CM, Alvord EC Jr. Cava septi pellucidi et vergae: their normal and pathogical states[J]. Brain, 1969, 92(1): 213-223. DOI: 10.1093/brain/92.1.213.
[2]
Hosseinzadeh K, Luo J, Borhani A, et al. Non-visualisation of cavum septi pellucidi: implication in prenatal diagnosis?[J]. Insights Imaging, 2013,4(3):357-367. DOI: 10.1007/s13244-013-0244-x.
[3]
Hagino H, Suzuki M, Kurokawa K, et al. Magnetic resonance imaging study of the cavum septi pellucidi in patients with schizophrenia[J]. Am J Psychiatry, 2001,158(10):1717-1719. DOI:10.1176/appi.ajp.158.10.1717.
[4]
Souweidane MM, Hoffman CE, Schwartz TH. Transcavum interforniceal endoscopic surgery of the third ventricle[J]. J Neurosurg Pediatr, 2008,2(4):231-236. DOI:10.3171/PED.2008.2.10.231.
[5]
Winter TC, Kennedy AM, Byrne J, et al. The cavum septi pellucidi: why is it important?[J]. J Ultrasound Med, 2010,29(3):427-444. DOI:10.7863/jum.2010.29.3.427.
Callen PW, Callen AL, Glenn OA, et al. Columns of the fornix, not to be mistaken for the cavum septi pellucidi on prenatal sonography[J]. J Ultrasound Med, 2008,27(1):25-31. DOI: 10.7863/jum.2008.27.1.25.
[8]
Sherer DM, Sokolovski M, Dalloul M, et al. Prenatal diagnosis of dilated cavum septum pellucidum et vergae[J]. Am J Perinatol, 2004,21(5):247-251. DOI: 10.1055/s-2004-829869.
[9]
Bronshtein M, Weiner Z. Prenatal diagnosis of dilated cava septi pellucidi et vergae: associated anomalies, differential diagnosis, and pregnancy outcome[J]. Obstet Gynecol, 1992,80(5):838-842.
[10]
Sarwar M. The septum pellucidum: normal and abnormal[J]. AJNR Am J Neuroradiol, 1989,10(5):989-1005.
Tubbs RS, Krishnamurthy S, Verma K, et al. Cavum velum interpositum, cavum septum pellucidum, and cavum vergae: a review[J]. Childs Nerv Syst, 2011,27(11):1927-1930. DOI: 10.1007/s00381-011-1457-2.
[14]
Winkler PA, Weis S, Büttner A, et al. The transcallosal interforniceal approach to the third ventricle: anatomic and microsurgical aspects[J]. Neurosurgery, 1997,40(5):973-981; discussion 981-982. DOI:10.1097/00006123-199705000-00020.
[15]
李光旭, 万伟庆, 王玉海, 等. 穹窿的显微解剖及其在经胼胝体-穹窿间入路中的应用[J].中华神经外科杂志,2014,30(12):1266-1270. DOI: 10.3760/cma.j.issn.1001-2346.2014.12.022. Li GX, Wan QW, Wang YM, et al. Microsurgical anatomy of fornix and its application in surgery of transcallosal-interforniceal approach[J]. Chin J Neurosurg, 2014, 30(12): 1266-1270. DOI:10.3760/cma.j.issn.1001-2346.2014.12.022.
[16]
Tsutsumi S, Ishii H, Ono H, et al. Visualization of the cavum septi pellucidi, cavum Vergae, and cavum veli interpositi using magnetic resonance imaging[J]. Surg Radiol Anat, 2018,40(2):159-164. DOI:10.1007/s00276-017-1935-7.
[17]
Wang KC, Fuh JL, Lirng JF, et al. Headache profiles in patients with a dilatated cyst of the cavum septi pellucidi[J]. Cephalalgia, 2004,24(10):867-874. DOI: 10.1111/j.1468-2982.2004.00760.x.
[18]
Schunk H. Congenital dilatations of the septum pellucidum[J]. Radiology, 1963, 81: 610-618. DOI:10.1148/81.4.610.
[19]
Schwidde JT. Incidence of cavum septi pellucidi and cavum Vergae in 1, 032 human brains[J]. AMA Arch Neurol Psychiatry, 1952, 67(5): 625-632.
[20]
Vitorino Araujo JL, Veiga J, Wen HT, et al. Comparative anatomical analysis of the transcallosal-transchoroidal and transcallosal-transforniceal-transchoroidal approaches to the third ventricle[J]. J Neurosurg, 2017,127(1):209-218. DOI:10.3171/2016.8.JNS16403.