Abstract：Objective This study was designed to analyze and compare the efficacy and outcomes of anterior cervical decompression and fusion (ACDF) using polyetheretherketone (PEEK) cages and titanium cage.Methods Reports of studies using case-control studies to compare the titanium cage and PEEK cage in ACDF were retrieved from the PubMed Library, Cochrane Library, Embase Library, China National Knowledge Internet and Wanfang Data from January 2007 to March 2017. Methodological quality of the studies was critically assessed. Statistical software Revman 5.0 was used for data-analysis.Results A total of 5 studies involved 361 patients were included. Among them, 4 literatures were high quality, and 1 was medium. The results showed that, when the efficacy of PEEK cage and titanium cage were compared in ACDF, there was statistical difference in the subsidence rate [odds ratio(OR)=3.49, 95%CI 1.75-6.99, P=0.0004]. However, there was no statistical significance in the fusion rate(OR=1.60, 95%CI 0.05-53.73, P=0.79), dislocation rate(OR=3.61, 95%CI 0.91-14.34, P=0.07), the average operation time[weighted mean difference(WMD)=0.87, 95%CI -24.95~26.69, P=0.95], the excellent and good rate of Odom index (OR=1.27, 95%CI 0.60-2.68, P=0.71), NDI(WMD=3.24, 95%CI -0.44-6.93, P=0.08)and Cobb angel of operated segment(WMD=-2.29, 95%CI -4.63-0.05, P=0.05).Conclusions The PEEk cage is superior to the titanium cage in ACDF in regards to the subsidence rate, but both cages achieve similar and satisfactory clinical effect in the ACDF.
周悦彬, 郭洪刚, 蔡志威, 梁玉柱. 钛金属cage与聚醚醚酮cage在颈前路减压融合术后临床疗效的Meta分析[J]. 中华解剖与临床杂志, 2018, 23(1): 39-44.
Zhou Yuebin, Guo Honggang, Cai Zhiwei, Liang Yuzhu. Clinical effect of titanium cage versus polyetheretherketone cage after the anterior cervical decompression and fusion:a Meta-analysis. Chinese Journal of Anatomy and Clinics, 2018, 23(1): 39-44.
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2018, Vol. 23 
