Abstract:Objective To investigate the relevant factors of transporting bone segment (TBS) retraction after external fixation removal before the union of the docking site in the treatment of tibial defect by bone transport.Methods A retrospective analysis was conducted on 41 cases with tibial bone defect who were treated by bone transport in our hospital and presented TBS retraction after the removal or failure of external fixation before the union of the docking site. The patients included 25 males and 16 females aged 18-71 (40±15) years. Pearson correlation was used to analyze the relationship between TBS retraction distance and nine indexes, namely, age, gender, time from injury to operation, bone defect length, number of operations, TBS size, transport distance, fixation time, and time interval between radiologic examinations before and after the removal or failure of external TBS fixation. Risk factors with significant level were further identified using multivariate linear regression.Results The time from injury to operation was 7-95 (40.54±25.65) days, the bone defect length was 5.0-11.0 (6.90±1.20) cm, the number of operations was 1-5 (1.64±0.82), the TBS size was 4.8-12.0 (9.68±2.24) cm, the transport distance was 4.5-11.0 (6.76±1.64) cm, the fixation time was 3.5-11.5 (7.47±1.94) months, the time interval was 5-21 (10.16±4.07) days, and the retraction distance was 1.5-30.0 (8.73±7.99) mm. Pearson correlation showed that fixation time was negatively correlated with retraction distance, whereas transport distance and TBS size were positively correlated with transport distance, and the differences were significant(r=-0.897, 0.501, 0.419; all P values<0.05). Differences in age, gender, time from injury to operation, bone defect length, and number of operations were not significant (all P values>0.05). The multivariate linear regression analysis of fixation time, transport distance, and TBS size showed that transport distance and fixation time were linear with retraction distance (t=-10.385, 3.027; both P<0.05), and the regression equation was: ^Yretraction distance(mm)=27.081-2.805Xfixation time(month)+0.447Xtransport distance(cm) (R2=0.805, F=13.256, P<0.01).Conclusions In the process of bone transport, the retraction distance is related to TBS size, transport distance, and fixation time, and fixation time and transport distance are linear with retraction distance.
周子红, 顾三军, 孙振中, 魏长宝, 殷渠东. 骨搬运治疗胫骨骨缺损中滑移段外固定取出后发生回缩现象的相关因素分析[J]. 中华解剖与临床杂志, 2021, 26(6): 668-673.
Zhou Zihong, Gu Sanjun, Sun Zhenzhong, Wei Changbao, Yin Qudong. Relevant factors analysis of transporting bone segment retraction after external fixation removal in the treatment of tibial defect by bone transport. Chinese Journal of Anatomy and Clinics, 2021, 26(6): 668-673.
Borzunov DY, Kolchin SN, Malkova TA. Role of the Ilizarov non-free bone plasty in the management of long bone defects and nonunion: problems solved and unsolved[J]. World J Orthop, 2020,11(6): 304-318. DOI:10.5312/wjo.v11.i6.304.
[2]
Fahad S, Habib AA, Awais MB, et al. Infected non-union of tibia treated with Ilizarov external fixator: our experience[J]. Malays Orthop J, 2019, 13(1): 36-41. DOI:10.5704/MOJ.1903.006.
[3]
Wu Y, Yin Q, Rui Y, et al.Ilizarov technique: bone transport versus bone shortening-lengthening for tibial bone and soft-tissue defects[J]. J Orthop Sci, 2018, 23(2): 341-345. DOI:org/10.1016/j.jos.2017.12.002.
Chen X, Zhang WT, Yu ZR, et al. Application of bone transport with unilateral external fixator combined with locked plate internal fixation in treatment of infected tibial nonunion[J]. Chinese Journal of Reconstructive and Reconstructive Surgery, 2019, 33(3): 328-331. DOI:10.7507/1002-1892.201811024.
Hu JZ, Shi ZY, Yang CZ, et al. Clinical study of bone transport combined with bone graft and internal fixation at the docking site in the treatment of large segmental bone defect in lower limb[J]. Chin J Orthop, 2018, 38(5): 280-287. DOI:10.3760/cma.j.issn.0253-2352.2018.05.004.
[6]
Olesen UK, Nygaard T, Prince DE, et al. Plate-assisted bone segment transport with motorized lengthening nails and locking plates: a technique to treat femoral and tibial bone Defects[J]. J Am Acad Orthop Surg Glob Res Rev, 2019, 3(8): e064. DOI:10.5435/JAAOSGlobal-D-19-00064.
[7]
Abdel-Aleem Ahmed AS, Abdelshafi Tabl E. Treatment of open intraarticular distal femur fractures by Ilizarov fixator; an approach to improve the outcome with mid-term results[J]. Injury, 2019, 50(10): 1731-1738. DOI:10.1016/j.injury.2019.05.011.
[8]
Lu Y, Ma T, Ren C, et al. Treatment of segmental tibial defects by bone transport with circular external fixation and a locking plate[J]. J Int Med Res, 2020, 48(4): 300060520920407. DOI:10.1177/0300060520920407.
[9]
Bas A, Daldal F, Eralp L, et al. Treatment of tibial and femoral bone defects with bone transport over an intramedullary nail[J]. J Orthop Trauma, 2020, 34(10): e353-e359. DOI:10.1097/BOT.0000000000001780.
[10]
Aktuglu K, Erol K, Vahabi A. Ilizarov bone transport and treatment of critical-sized tibial bone defects: a narrative review[J]. J Orthop Traumatol, 2019, 20(1): 22. DOI:10.1186/s10195-019-0527-1.
Cheng GY, Lin QR, Zhou CH, et al. Proximal versus distal tibial bone transport in the treatment of chronic tibial osteomyelitis[J]. Chin J Orthop Trauma, 2020, 22(5): 379-383.DOI:10.3760/cma.j.cn115530-20190815-00284.
Li ZT, Zhao QB, Cai Y, et al. Comparison of efficacy between unilateral external fixator and circular external fixator in treatment of femoral osteomyelitis with bone defect[J]. Chin J Bone Joint Injury, 2020, 35(12): 1253-1256. DOI:10.7531/j.issn.1672-9935.2020.12.007.
Wang ZH, Gao JQ, Zhan XH, et al. One-stage debridement and two-stage Ilizarov bone transport technology for post-traumatic lateral malleolus defect[J]. Chinese Journal of Reparative and Reconstructive Surgery, 2019, 33(7): 865-870. DOI:10.7507/1002-1892.201901091.
[14]
Oztürkmen Y, Karamehmetoğlu M, Karadeniz H, et al. Acute treatment of segmental tibial fractures with the Ilizarov method[J]. Injury, 2009, 40(3): 321-326. DOI:10.1016/j.injury.2008.07.013.
[15]
Baumgart R, Kuhn V, Hinterwimmer S, et al. Tractive force measurement in bone transport—an in vivo investigation in humans[J]. Biomed Tech (Berl), 2004, 49(9): 248-256. DOI:10.1515/BMT.2004.047.
[16]
Horas K, Schnettler R, Maier G, et al. A novel intramedullary callus distraction system for the treatment of femoral bone defects[J]. Strategies Trauma Limb Reconstr, 2016, 11(2): 113-121. DOI:10.1007/s11751-016-0255-5.
[17]
Mora-Macías J, Reina-Romo E, Domínguez J. Model of the distraction callus tissue behavior during bone transport based in experiments in vivo[J]. J Mech Behav Biomed Mater, 2016, 61: 419-430. DOI:10.1016/j.jmbbm.2016.04.016.
[18]
Horas K, Schnettler R, Maier G, et al. The role of soft-tissue traction forces in bone segment transport for callus distraction: a force measurement cadaver study on eight human femora using a novel intramedullary callus distraction system[J]. Strategies Trauma Limb Reconstr, 2015, 10(1): 21-26. DOI:10.1007/s11751-015-0220-8.
[19]
Brunner UH, Cordey J, Schweiberer L, et al. Force required for bone segment transport in the treatment of large bone defects using medullary nail fixation[J]. Clin Orthop Relat Res, 1994 (301): 147-155.
[20]
Meyers N, Schülke J, Ignatius A, et al. Novel systems for the application of isolated tensile, compressive, and shearing stimulation of distraction callus tissue[J]. PLoS One, 2017, 12(12): e0189432. DOI:10.1371/journal.pone.0189432.
[21]
Aronson J, Harp JH. Mechanical forces as predictors of healing during tibial lengthening by distraction osteogenesis[J]. Clin Orthop Relat Res, 1994(301): 73-79.
[22]
Leong JC, Ma RY, Clark JA, et al. Viscoelastic behavior of tissue in leg lengthening by distraction[J]. Clin Orthop Relat Res, 1979(139): 102-109.
[23]
Yang Z, Tao H, Ye Z, et al. Bone transport for reconstruction of large bone defects after tibial tumor resection: a report of five cases[J]. J Int Med Res, 2018, 46(8): 3219-3225. DOI:10.1177/0300060518774992.
Wang JB, Gu SJ, Zhou ZH, et al. Bone transport versus induced membrane technique for large segmental tibial defects[J]. Chin J Orthop Trauma, 2019, 21(5): 398-404. DOI:10.3760/cma.j.issn.1671-7600.2019.05.007.