Abstract：Objective To explore the risk factors of intolerable cough after pneumonectomy (ICAP). Methods A retrospective cohort study was conducted. The clinical data of 365 patients who underwent pneumonectomy in the First Affiliated Hospital of Bengbu Medical College from January to December 2019 were included. There were 211 males and 154 females aged 24-83 years old. According to the occurrence of ICAP after operation, the patients were divided into the ICAP group (61 patients) and non-ICAP group (304 patients). Univariate analysis and multivariate logistic regression analysis were used to explore the risk factors of ICAP after pneumonectomy. Results Univariate analysis showed that there were significant differences in gender, smoking history, lymph node resection around the tracheal tree, preoperative cough, and surgical side between the two groups (χ2=8.50, 15.25, 12.15, 4.20, 4.95, respectively; all P values < 0.05). Multivariate logistic regression analysis showed that gender, smoking history, operation side, peritracheal tree lymph node resection, and preoperative cough were independent risk factors for ICAP (odds ratio=4.036, 6.243, 2.311, 3.347, 1.953; 95% confidence interval 2.077-7.845, 3.030-12.864, 1.184-4.512, 1.732-6.467, 1.039-3.668, respectively; all P values <0.05). Conclusion Gender, smoking history, operation side, peritracheal tree lymph node resection, and preoperative cough were risk factors for ICAP.
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2022, Vol. 27 
