Comparison of ultrosound and contrast-enhanced CT in the diagnosis of cervical lymph nodes metastasis in patients with thyriod carcinoma: A meta-analysis
Li Hongwen, Xie Xinhui, Liu Bin, Wu Xingwang
Department of Radiology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China
Abstract：Objective To evaluate the clinical value of ultrasound (US) and contrast-enhanced CT(CECT) in the diagnosis of cervical lymph nodes metastasis in patients with thyroid carcinoma by a meta-analysis.Methods Literature search was performed in Medline, Embase, Cochrane, CBM datebases to identify relevant English and Chinese literatures with pathological result as the gold standard from January 1995 to December 2012. The quality of each selected study was evaluated by QUADAS. The Meta-disc 1.4 software was used to calculate the pooled sensitivity, specificity and the corresponding 95% CI. Summary receiver operating characteristic curves (ROC), area under curve (AUC) and the Q* index were calculated and used to evaluate the diagnostic efficiency of the two Methods by Z test.Results Totally seventeen literatures (1 682 patients) were included, the pooled sensitivity and specificity for and CECT scanning were 0.62, 0.61 and 0.92, 0.86. The AUC of the two were 0.84, 0.82 respectively. There was no statistically significant difference between US and CT (P=0.78) in the Q* index(0.7718, 0.7561).Conclusions US and CECT have similar value in the diagnosis of cervical lymph nodes metastasis in patients with thyroid carcinoma, but there is higher specificity in US than that in CECT.
李红文,谢新晖,刘斌,吴兴旺. 超声、增强CT诊断甲状腺癌颈部淋巴结转移比较的Meta分析[J]. 中华解剖与临床杂志, 2014, 19(5): 399-405.
Li Hongwen, Xie Xinhui, Liu Bin, Wu Xingwang. Comparison of ultrosound and contrast-enhanced CT in the diagnosis of cervical lymph nodes metastasis in patients with thyriod carcinoma: A meta-analysis. Chinese Journal of Anatomy and Clinics, 2014, 19(5): 399-405.
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2014, Vol. 19 
