Micro-hardness distribution of humeral shaft in human skeleton
Zhang Xiaojuan1,2,3, Li Sheng1,2,3, Wu Weiwei1,2,3, Liu Guobin1,2,3, Wang Jianzhao1,2,3, Yin Bing1,2,3, Hu Zusheng1,2,3, Fu Lei2, Zhang Yingze1,2,3
1Department of Orthopaedic Surgery, the Third Hospital of Hebei Medical University, Shijiazhuang 050051; 2Orthopaedic Research Institution of Hebei Province, Shijiazhuang 050051; 3Key Laboratory of Biomechanics of Hebei Province;Shijiazhuang 050051
Abstract：Objective To measure and analyze the distribution and significance of bone hardness at different levels and directions of humerus shaft.Methods Three right humeral shafts from fresh cadaver specimens were included in this study, and were divided into 7 sections perpendicular to the long axis of the humeral shaft.Then,7 layers (3 mm specimen) were cut with diamond saw, and then divided into humerus upper segment(Ⅰ, Ⅱ layer), middle segment(Ⅲ-Ⅴ layer), lower segment(Ⅵ, Ⅶ layer), and each layer was divided into anterior, posterior, medial and lateral four areas. Vickers microhardness diamond pressure head was used in the specimen surface to achieve hardness measurement. The distribution of hardness was recorded and analyzed.Results A total of 84 parts of humeral shaft were measured and 420 measurements were made. The average hardness of humeral shaft was (47.52±6.01) HV. The overall hardness of the middle humeral shaft was greater than that of the upper and lower humeral shaft(F=11.594, P＜0.01). Ⅳ level of 7 horizontal layers had the maximum hardness (51.34±7.01) HV. Minimum hardness was Ⅶ level (45.72±6.25) HV. The medial part of middle shaft Ⅳhardness was biggest (53.77±8.70) HV, and the minimum hardness occurred in posterior part of shaft section Ⅶ (42.02±7.47 mm) HV. The overall hardness of the posterior humerus (45.28±6.47) HV was lower than that of the lateral humerus (49.12±5.22) HV, the medial humerus (48.28±6.10)HV, and the anterior humerus (47.40±5.55)HV (F=8.347, P＜0.01).Conclusions There are differences in the micro-hardness of the humerus diaphyseal cortex at different levels and in the orientation of the bone. The data of this distribution can be used to guide the design of 3D-printed implants adapted to the characteristics of bone stress conduction under physiological conditions. It can also provide data support for bone modeling and finite element analysis of bone biomechanical properties under simulated physiological state.
张晓娟, 李升, 吴卫卫, 刘国彬, 王建朝, 殷兵, 胡祖圣, 付蕾, 张英泽. 人体肱骨干显微骨硬度分布特征的实验研究[J]. 中华解剖与临床杂志, 2019, 24(4): 318-321.
Zhang Xiaojuan, Li Sheng, Wu Weiwei, Liu Guobin, Wang Jianzhao, Yin Bing, Hu Zusheng, Fu Lei, Zhang Yingze. Micro-hardness distribution of humeral shaft in human skeleton. Chinese Journal of Anatomy and Clinics, 2019, 24(4): 318-321.
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2019, Vol. 24 
