Abstract：Although the application of megaprosthesis has maturely progressed, complications of aseptic loosening, breakage, and infection could not be satisfactorily solved and prominently influence the therapeutic effect and prognosis of patients. The development of biological materials, surface processing techniques, and biomechanics theoretically supports the improvement of megaprosthesis design. The present orientation which is focused on includes the improvement of surface coating technics for megaprosthesis, application of antibacterial processing which could decrease the occurrence of infection and amelioration of fixation by the optimization of structural design.
通讯作者:
郭卫,主任医师,教授,博士生导师。现任北京大学人民医院骨肿瘤诊疗中心主任,北京大学人民医院骨科教研室主任,骨肿瘤研究室主任。亚太地区骨肿瘤学会（APMSTS）前任主席,国际保肢学会（ISOLS）前任主席,国际骶骨骨盆肿瘤研究协作组主席,儿童肿瘤协作组（COG）成员,东亚骨与软组织肿瘤研究协作组（EMOG）成员,国际结缔组织肿瘤协会成员,中华医学会骨科学分会骨肿瘤学组组长（2005—2017年）,中华医学会肿瘤学分会骨肿瘤学组组长,中华医学会骨科学分会委员,中国医师学会骨科分会常委,中国医师学会骨科分会骨肿瘤专业委员会主任委员,J Bone and Joint Surg副主编,Chinese Medical Journal编委、《中华骨科杂志》编委、《中华外科杂志》编委、Journal of Orthopaedic Science编委等。担任多项国家级科研项目、国际合作项目负责人。获得各类奖项10项,主持原发恶性骨肿瘤的规范化切除及功能重建的系列研究获得国家科技进步二等奖。近年来共发表300余篇高水平论文,其中SCI收录100余篇,主编了世界范围内第一部关于骨盆环肿瘤切除重建技术的专著《骨盆肿瘤外科学》。主持制定了骨肉瘤、软骨肉瘤、骨巨细胞瘤、尤文肉瘤和骨髓瘤的循证医学诊疗指南。Email：bonetumor@163.com
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